Kate Mulgrew as a glamorous actress with a dead body guard.
George Clooney as a good-looking guy who maybe doesn’t get enough sleep.
Charlotte Rae as a soured socialite.
Robert Reed as creepy Alex Trebek (apparently).
Billy Zane as a guy living it up while he still has a good head of hair.
Megan Mullaly as a high-minded lawyer who dresses like Diane Chambers. Really, her outfits steal the episode. I can’t imagine what the tactic was in dressing her in this manner, but for god’s sakes, lookit.
Jessica Walter as a proto-Lucille Bluth, basically, who also dresses exactly how Lucille Bluth would have dressed in the ’80s.
Time-traveling Kate McKinnon (apparently)
Florence Henderson as a hot shit fashion designer.
Courteney Cox as a prim bride pushed to the edge in a circus-themed episode.
Linda Hamilton and Bryan Cranston as ill-fated lovebirds in a tennis-themed episode.
Eve Plumb, a.k.a. Jan Brady from The Brady Bunch (right) as a hardened prison inmate named Tug.
James Marshall, a.k.a. James Hurley from Twin Peaks.
And Meg Foster, a.k.a. Evil-Lyn from Masters of the Universe.
EDIT: I’m just going to tack on subsequent Murder, She Wrote celeb sightings to the bottom of this post. Enjoy.
There’s also young Conchata Ferrell, more or less playing the type of role she plays as old Conchata Ferrell.
Pamela Voorhees herself, Betsy Palmer.
And time-traveling Maria Bamford (again, apparently).