A far more impressive name for a disease that leaves an impression on you. Also something that sounds like it came from a Harry Potter novel. Next time you get syphilis, try telling your friends that you have grandgore instead. They'll respect you for it.
grandgore — noun: a Scottish word for "syphilis"
The first webpage of note that features this word is the Wikipedia page for Inchgarvie, a Scottish island that, under the Grandgore Act of 1497, became a place of "compulsory retirement" for syphilitics. Speaking of shades of connotation, "retirement" has a much nicer ring to it than "quarantine."
[ Source: Weird and Wonderful Words ]